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. 2019 Jan;42(1):86-93.
doi: 10.1080/10790268.2017.1423266. Epub 2018 Jan 11.

Prevalence of metabolic syndrome in veterans with spinal cord injury

David R Gater Jr  1 , Gary J Farkas  1 , Arthur S Berg  2 , Camilo Castillo  3
Affiliations

Prevalence of metabolic syndrome in veterans with spinal cord injury

David R Gater Jr et al. J Spinal Cord Med. 2019 Jan.

Abstract

Context/objective: Recent literature would suggest the prevalence of metabolic syndrome in persons with spinal cord injury (SCI) is higher than that of the general population, although no large cohorts have yet been reported. Part of the controversy relates to the differing definitions provided for metabolic syndrome and the characterization of obesity in persons with SCI.

Design/participants: The current retrospective investigation represents a cross-sectional cohort of 473 veterans with SCI from a single center in the mid-Atlantic region of the United States for whom modified International Diabetes Federation (IDF) criterion variables for the metabolic syndrome were available in the computerized personal record system (CPRS).

Outcome measures: These variables included a surrogate marker of obesity appropriate to SCI (Body Mass Index (BMI) ≥ 22 kg/m2), as well as indicators of diabetes, dyslipidemia and hypertension.

Results: Over 57% of the veterans assessed were determined to have metabolic syndrome by modified IDF criteria, including 76.7% with BMI ≥ 22 kg/m2, 55.1% with or under treatment for hypertension, 49.7% with or previously diagnosed with diabetes mellitus, and 69.7% with or under treatment for high density lipoprotein (HDL) cholesterol under 40 mg/dl.

Conclusion: Metabolic syndrome and its constituent components appear to be more prevalent in veterans with SCI than in the general population, suggesting a greater need for identification and treatment interventions in this specialty population.

Keywords: Metabolic syndrome; Obesity; Spinal cord injury.

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References

    1. Grundy SM.A changing paradigm for prevention of cardiovascular disease: emergence of the metabolic syndrome as a multiplex risk factor. Eur Heart J 2008;10(B):B16–B23. doi: 10.1093/eurheartj/sum044 - DOI
    1. Tune JD, Goodwill AG, Sassoon DJ, Mather KJ.. Cardiovascular consequences of metabolic syndrome. Transl Res 2017;183:57–70. doi: 10.1016/j.trsl.2017.01.001 - DOI - PMC - PubMed
    1. Farkas GJ, Gater DR.. Neurogenic obesity and systemic inflammation following spinal cord injury: a review. J Spinal Cord Med 2017:1–10. - PMC - PubMed
    1. Alberti K, Zimmet PZ.. Definition, diagnosis and classification of diabetes mellitus and its complications part 1: Diagnosis and classification of diabetes mellitus - Provisional report of a WHO consultation. Diabetic Med 1998;15(7):539–53. doi: 10.1002/(SICI)1096-9136(199807)15:7<539::AID-DIA668>3.0.CO;2-S - DOI - PubMed
    1. Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Final Report. Circulation 2002;106(25):3143–3421. - PubMed

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