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Case Reports
. 2018 Jan 2:23:16-19.
doi: 10.1016/j.gore.2017.12.006. eCollection 2018 Feb.

Cervical clear cell adenocarcinoma with an exceptionally low proliferation index: Report of a case

Mary G Dandulakis  1 , Aidas J Mattis  1 , Andrea R Hagemann  2 , Ian S Hagemann  1   2
Affiliations
Case Reports

Cervical clear cell adenocarcinoma with an exceptionally low proliferation index: Report of a case

Mary G Dandulakis et al. Gynecol Oncol Rep. .

Erratum in

Abstract

•A histologically low-grade cervical clear cell lesion was observed.•Proliferating cells were seen only at the periphery of this lesion.•Due to its low proliferation index, this may represent a precursor of clear cell carcinoma.•Further definition of such lesions may allow for more minimal management.

Keywords: Cervical cancer; Clear cell adenocarcinoma; Pathology; Precancerous conditions; Proliferation index.

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Figures

Fig. 1
Fig. 1
(A) Low-power photomicrograph of clear cell lesion in LEEP specimen (original magnification 20 ×). (B) Low-power photomicrograph illustrating cysts lined by bland, flattened cells, with eosinophilic luminal secretions (100 ×). (C) Rare cells with higher nuclear-to-cytoplasmic ratio and atypical nuclear features (200 ×). (D) Intracystic papillary projections (200 ×).
Fig. 2
Fig. 2
Representative immunostains performed on the LEEP specimen. (A) ER (original magnification 400 ×). (B) p53 (200 ×). (C) Napsin A (200 ×). (D) Ki-67 (100 ×).
See this image and copyright information in PMC

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