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. 1985 Sep;35(3):348-53.
doi: 10.1111/j.1600-0609.1985.tb01718.x.

Follow-up of normal individuals with a positive antiglobulin test

D Bareford, G Longster, L Gilks, L A Tovey

Follow-up of normal individuals with a positive antiglobulin test

D Bareford et al. Scand J Haematol. 1985 Sep.

Abstract

Over a period of 20 yr (1962-1982), 67 apparently fit donors at a Regional Blood Transfusion Service were found to have an unexplained positive direct antiglobulin test (DAT). During 1983, 26 were traced and re-tested. 9 still had a positive DAT only 1 of whom had developed autoimmune haemolytic anaemia. 17 had become negative though in 7 of these an autoantibody could still be detected by an enzyme technique. Unlike patients with established autoimmune disorders, the positive DAT individuals were found to have normal T cell subsets though B cells were significantly increased.

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