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Comment
. 2018 Jan 10;20(1):143-144.
doi: 10.1093/neuonc/nox194.

Comment on "Response assessment in medulloblastoma and leptomeningeal seeding tumors: recommendations from the Response Assessment in Pediatric Neuro-Oncology Committee"

Julie H Harreld  1
Affiliations
Comment

Comment on "Response assessment in medulloblastoma and leptomeningeal seeding tumors: recommendations from the Response Assessment in Pediatric Neuro-Oncology Committee"

Julie H Harreld. Neuro Oncol. .
No abstract available

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Figures

Fig. 1
Fig. 1
A 17 year-old male with medulloblastoma. Initial MRI performed with (A) sagittal T1 TSE with contrast, 3 mm thick/0.3 mm gap, and (B) axial T1 TSE with contrast, 3 mm thick/1.11 mm gap, was interpreted as negative for metastasis. Repeat MRI 18 days later with (C) sagittal T1 fluid attenuated inversion recovery (FLAIR) with contrast, 3 mm thick/0 gap, and (D) axial 3D T1 VIBE with contrast, reconstructed at 3 mm/0 gap, shows extensive leptomeningeal metastases (arrows), which were present in retrospect on the initial examination but obscured by CSF T1 hyperintensity and pulsation artifact typical of 3T and TSE techniques, respectively. Note the absence of CSF artifact on T1 FLAIR and VIBE, despite interleaving and 0 gap on T1 FLAIR. Gradient echo techniques such as VIBE are inherently less susceptible to CSF pulsation artifact than spin echo (SE/TSE/FSE).
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References

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