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Review
. 2018 Jan-Feb;31(1):24-34.
doi: 10.20524/aog.2017.0218. Epub 2017 Nov 27.

Colorectal polyposis and inherited colorectal cancer syndromes

Raphael M Byrne  1 , Vassiliki Liana Tsikitis  1
Affiliations
Review

Colorectal polyposis and inherited colorectal cancer syndromes

Raphael M Byrne et al. Ann Gastroenterol. 2018 Jan-Feb.

Abstract

The majority of colorectal cancer (CRC) cases are sporadic, with hereditary factors contributing to approximately 35% of CRC cases. Less than 5% of CRC is associated with a known genetic syndrome. Although adenomatous polyposis syndromes, hamartomatous polyposis syndromes, and those previously classified as non-polyposis CRC syndromes are quite rare, it is important for clinicians to know the characteristics of each syndrome and to understand the differences in cancer risks between the different conditions. This information is very important when treatment and surveillance plans are formulated for each individual patient.

Keywords: Adenomatous polyposis syndromes; cancer risk; colorectal cancer; hamartomatous polyposis syndromes; nonpolyposis colorectal cancer syndromes.

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Conflict of interest statement

Conflict of Interest: None

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