Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Dec;52(4):324-326.
doi: 10.5045/br.2017.52.4.324. Epub 2017 Dec 26.

A case of primary plasma cell leukemia exhibiting hemophagocytic plasma cells relapsed with multiple cutaneous plasmacytoma

Affiliations

A case of primary plasma cell leukemia exhibiting hemophagocytic plasma cells relapsed with multiple cutaneous plasmacytoma

Narae Hwang et al. Blood Res. 2017 Dec.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Authors' Disclosures of Potential Conflicts of Interest: No potential conflicts of interest relevant to this article were reported.

Figures

Fig. 1
Fig. 1. Hemophagocytic plasma cells and abnormal karyotyping result. (A) Microscopic examination of bone marrow (BM) showing large, bizarre plasma cells with characteristic hemophagocytic features mostly with mature erythrocytes and platelets (Wright-Giemsa staining, ×1,000). (B) Conventional BM chromosome analysis result showing 45,X,−X,+1,dic(1;8)(p13;p23),del(6)(q22q25), del(8)(p21) karyotype.
Fig. 2
Fig. 2. Multiple skin nodules and their biopsy showing infiltration of plasma cells. Multiple skin nodules in the patient's extremities (A). Biopsy of the skin-infiltrating plasma cells showing positive immunohistochemical staining for CD138 (B) and lambda light-chain (C) (×200).

Similar articles

Cited by

References

    1. Deng S, Xu Y, An G, et al. Features of extramedullary disease of multiple myeloma: high frequency of p53 deletion and poor survival: a retrospective single-center study of 834 cases. Clin Lymphoma Myeloma Leuk. 2015;15:286–291. - PubMed
    1. Swerdlow SH, Campo E, Harris NL, editors. WHO classification of tumours of haematopoietic and lymphoid tissues. 4th ed. Lyon, France: IARC Press; 2008.
    1. Invernizzi R, Pecci A. A case of phagocytic multiple myeloma. Haematologica. 2000;85:318. - PubMed
    1. Kanoh T, Saigo K. Phagocytic myeloma cells in asymptomatic multiple myeloma. Tohoku J Exp Med. 1987;153:207–210. - PubMed
    1. Kucukkaya RD, Hacihanefioglu A, Yenerel MN, et al. CD15-expressing phagocytic plasma cells in a patient with multiple myeloma. Blood. 2001;97:581–583. - PubMed

LinkOut - more resources