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. 2018 Jan 15;11(1):30.
doi: 10.1186/s13104-018-3167-2.

Prevalence of a carbapenem-resistance gene (KPC), vancomycin-resistance genes (van A/B) and a methicillin-resistance gene (mecA) in hospital and municipal sewage in a southwestern province of Saudi Arabia

Vinod Kumar Basode  1 , Ahmed Abdulhaq  2   3 , Mohammed Uthman A Alamoudi  2 , Hassan Mohammad Tohari  2 , Waleed Ali Quhal  2 , Aymen Mohammed Madkhali  2 , Yahya Hasan Hobani  4 , Almonther Abdullah Hershan  5
Affiliations

Prevalence of a carbapenem-resistance gene (KPC), vancomycin-resistance genes (van A/B) and a methicillin-resistance gene (mecA) in hospital and municipal sewage in a southwestern province of Saudi Arabia

Vinod Kumar Basode et al. BMC Res Notes. .

Abstract

Objective: According to the World Health Organization, the increasing antibiotic resistance of pathogens is one of the most important threats to human health. Prevalence of a carbapenem-resistance gene (KPC), vancomycin-resistance genes (van A/B) and a methicillin-resistance gene (mecA) in hospital and municipal sewages will be potential threat to public health.

Results: Vancomycin-resistance genes were detected in the sewage of community tank-II, sewage tank of the tertiary and general hospital. Carbapenem-resistance gene was detected in sewage of community tank-II and sewage from tertiary hospital. Methicillin-resistance gene was detected in sewage of community tank-II, sewage from a fish market sewage tank and sewage from an animal slaughter house sewage tank. The detection of a KPC, van A/B and a mecA in sewages will help further the process to take the appropriate measures to prevent the spread of such bacteria in the environment.

Keywords: Carbapenem-resistance gene; Methicillin resistance gene; Sewage; Vancomycin-resistance genes.

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