Bone lead levels in an environmentally exposed elderly population in shanghai, China
- PMID: 29335178
- PMCID: PMC10613101
- DOI: 10.1016/j.scitotenv.2018.01.091
Bone lead levels in an environmentally exposed elderly population in shanghai, China
Abstract
This study looked at measurements of lead (Pb) in a pilot population of environmentally exposed elderly residents of Shanghai, China and presented the first set of bone Pb data on an elderly Chinese population. We found that with environmental exposures in this population using K-shell x-ray fluorescence (KXRF) bone Pb measurements 40% of the individuals had bone Pb levels above the nominal detection limit with an average bone lead level of 4.9 ± 3.6 μg/g. This bone lead level is lower than comparable values from previous studies of community dwelling adults in US cities. This population had a slightly higher geometric mean blood Pb of 2.6 μg/dL than the adult US population. The main conclusion of this data is that in Shanghai there is environmental exposure to Pb, measured through blood and bone, which should be further investigated to assess the health impact of this exposure.
Keywords: Biomonitoring; Bone lead; Cumulative; Environmental monitoring; Lead; Metals.
Copyright © 2018. Published by Elsevier B.V.
Figures
Similar articles
-
XRF-measured bone lead (Pb) as a biomarker for Pb exposure and toxicity among children diagnosed with Pb poisoning.Biomarkers. 2016;21(4):347-52. doi: 10.3109/1354750X.2016.1139183. Epub 2016 Feb 9. Biomarkers. 2016. PMID: 26856822 Free PMC article.
-
Bone lead content assessed by L-line x-ray fluorescence in lead-exposed and non-lead-exposed suburban populations in the United States.Proc Natl Acad Sci U S A. 1993 Apr 1;90(7):2789-92. doi: 10.1073/pnas.90.7.2789. Proc Natl Acad Sci U S A. 1993. PMID: 8464891 Free PMC article.
-
Evaluation of a portable XRF device for in vivo quantification of lead in bone among a US population.Sci Total Environ. 2021 Jan 20;753:142351. doi: 10.1016/j.scitotenv.2020.142351. Epub 2020 Sep 11. Sci Total Environ. 2021. PMID: 33207470 Free PMC article.
-
Portable x-ray fluorescence for bone lead measurement: Current approaches and future directions.Curr Environ Health Rep. 2024 Sep;11(3):443-451. doi: 10.1007/s40572-024-00450-x. Epub 2024 May 22. Curr Environ Health Rep. 2024. PMID: 38776000 Review.
-
The epidemiology of lead toxicity in adults: measuring dose and consideration of other methodologic issues.Environ Health Perspect. 2007 Mar;115(3):455-62. doi: 10.1289/ehp.9783. Epub 2006 Dec 22. Environ Health Perspect. 2007. PMID: 17431499 Free PMC article. Review.
Cited by
-
Blood lead, bone lead and child attention-deficit-hyperactivity-disorder-like behavior.Sci Total Environ. 2019 Apr 1;659:161-167. doi: 10.1016/j.scitotenv.2018.12.219. Epub 2018 Dec 15. Sci Total Environ. 2019. PMID: 30597466 Free PMC article.
-
Lead exposure and association with angiogenic factors and hypertensive disorders of pregnancy.Pregnancy Hypertens. 2020 Oct;22:93-98. doi: 10.1016/j.preghy.2020.07.014. Epub 2020 Jul 31. Pregnancy Hypertens. 2020. PMID: 32763807 Free PMC article.
-
Dosimetry Testing for a New In Vivo X-ray Fluorescence Measurement System.Health Phys. 2025 Apr 1;128(4):273-278. doi: 10.1097/HP.0000000000001839. Epub 2024 May 27. Health Phys. 2025. PMID: 39999410
-
Cognitive Impairment Induced by Lead Exposure during Lifespan: Mechanisms of Lead Neurotoxicity.Toxics. 2021 Jan 28;9(2):23. doi: 10.3390/toxics9020023. Toxics. 2021. PMID: 33525464 Free PMC article. Review.
References
-
- Navas-Acien A, Schwartz BS, Rothenberg SJ, Hu H, Silbergeld EK, Guallar E. Bone lead levels and blood pressure endpoints. Epidemiology. 2008;19:8. - PubMed
-
- Nie H. Studies in bone lead: A new cadmium-109 XRF measurement system. Modeling bone lead metabolism. Interpreting low concentration data [Thesis (Ph D)]: McMaster University; (Canada: ), 2005.; 2005.
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources