Genetics of lipid metabolism in prostate cancer

Affiliations

¹ Centre for Cancer Research and Cell Biology, Queen's University of Belfast, Belfast, UK.
² Centre for Cancer Research and Cell Biology, Queen's University of Belfast, Belfast, UK. i.mills@qub.ac.uk.
³ Nuffield Department of Surgical Sciences, John Radcliffe Hospital, University of Oxford, Oxford, UK. i.mills@qub.ac.uk.

Comment

Ninu Poulose et al. Nat Genet. 2018 Feb.

. 2018 Feb;50(2):169-171.

doi: 10.1038/s41588-017-0037-0.

¹ Centre for Cancer Research and Cell Biology, Queen's University of Belfast, Belfast, UK.
² Centre for Cancer Research and Cell Biology, Queen's University of Belfast, Belfast, UK. i.mills@qub.ac.uk.
³ Nuffield Department of Surgical Sciences, John Radcliffe Hospital, University of Oxford, Oxford, UK. i.mills@qub.ac.uk.

No abstract available

Comment on

Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer.
Chen J, Guccini I, Di Mitri D, Brina D, Revandkar A, Sarti M, Pasquini E, Alajati A, Pinton S, Losa M, Civenni G, Catapano CV, Sgrignani J, Cavalli A, D'Antuono R, Asara JM, Morandi A, Chiarugi P, Crotti S, Agostini M, Montopoli M, Masgras I, Rasola A, Garcia-Escudero R, Delaleu N, Rinaldi A, Bertoni F, Bono J, Carracedo A, Alimonti A. Chen J, et al. Nat Genet. 2018 Feb;50(2):219-228. doi: 10.1038/s41588-017-0026-3. Epub 2018 Jan 15. Nat Genet. 2018. PMID: 29335542 Free PMC article.
An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer.
Chen M, Zhang J, Sampieri K, Clohessy JG, Mendez L, Gonzalez-Billalabeitia E, Liu XS, Lee YR, Fung J, Katon JM, Menon AV, Webster KA, Ng C, Palumbieri MD, Diolombi MS, Breitkopf SB, Teruya-Feldstein J, Signoretti S, Bronson RT, Asara JM, Castillo-Martin M, Cordon-Cardo C, Pandolfi PP. Chen M, et al. Nat Genet. 2018 Feb;50(2):206-218. doi: 10.1038/s41588-017-0027-2. Epub 2018 Jan 15. Nat Genet. 2018. PMID: 29335545 Free PMC article.