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. 2018 Jun;30(6):727-733.
doi: 10.1080/09540121.2018.1425363. Epub 2018 Jan 16.

Adherence to antiretroviral therapy, stigma and behavioral risk factors in HIV-infected adolescents in Asia

Wasana Prasitsuebsai  1 , Chuenkamol Sethaputra  2 , Pagakrong Lumbiganon  3 , Rawiwan Hansudewechakul  4 , Kulkanya Chokephaibulkit  5 , Khanh Huu Truong  6 , Lam Van Nguyen  7 , Kamarul Azahar Mohd Razali  8 , Nik Khairulddin Nik Yusoff  9 , Moy Siew Fong  10 , Sirinya Teeraananchai  1 , Jintanat Ananworanich  11   12   13   14 , Nicolas Durier  2   15 ; TApHOD ACASI study group of IeDEA Asia-Pacific
Affiliations

Adherence to antiretroviral therapy, stigma and behavioral risk factors in HIV-infected adolescents in Asia

Wasana Prasitsuebsai et al. AIDS Care. 2018 Jun.

Abstract

We studied behavioral risks among HIV-infected and uninfected adolescents using an audio computer-assisted self-interview. A prospective cohort study was initiated between 2013 and 2014 in Malaysia, Thailand, and Vietnam. HIV-infected adolescents were matched to uninfected adolescents (4:1) by sex and age group (12-14 and 15-18 years). We enrolled 250 HIV-infected (48% male; median age 14.5 years; 93% perinatally infected) and 59 uninfected (51% male; median age 14.1 years) adolescents. At enrollment, HIV-infected adolescents were on antiretroviral therapy (ART) for a median (IQR) of 7.5 (4.7-10.2) years, and 14% had HIV-RNA >1000 copies/mL; 19% reported adherence <80%. Eighty-four (34%) HIV-infected and 26 (44%) uninfected adolescents reported having ever smoked cigarettes or drunk alcohol (p = 0.13); 10% of HIV-infected and 17% of uninfected adolescents reported having initiated sexual activity; 6 of the HIV-infected adolescents had HIV-RNA >1000 copies/mL. Risk behaviors were common among adolescents, with few differences between those with and without HIV.

Keywords: Asia; HIV; adherence; adolescents; stigma.

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Conflict of interest statement

Disclosure Statement

The authors declare no conflicts of interest related to this study.

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