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. 2018 Jan;19(1):50-57.
doi: 10.14744/AnatolJCardiol.2017.7949.

Assessment of the relationship between reperfusion success and T-peak to T-end interval in patients with ST elevation myocardial infarction treated with percutaneous coronary intervention

Metin Çağdaş  1 , Süleyman Karakoyun, İbrahim Rencüzoğulları, Yavuz Karabağ, Mahmut Yesin, Yalçın Velibey, İnanç Artaç, Doğan İliş, Süleyman Çağan Efe, Onur Taşar, Halil İbrahim Tanboğa
Affiliations

Assessment of the relationship between reperfusion success and T-peak to T-end interval in patients with ST elevation myocardial infarction treated with percutaneous coronary intervention

Metin Çağdaş et al. Anatol J Cardiol. 2018 Jan.

Abstract

Objective: T-peak-T-end (TPE) interval, which represents the dispersion of repolarization, is defined as the interval between the peak and end of the T-wave, and is associated with increased malignant ventricular arrhythmia and sudden cardiac death (SCD) in patients with ST elevation myocardial infarction (STEMI). Although prolonged TPE interval is associated with poor short- and long-term outcomes, even in patients with STEMI treated with successful primary percutaneous coronary intervention (pPCI), clinical, angiographic, and laboratory parameters that affect TPE remain to be elucidated. The aim of our study was to evaluate the potential relationship between prolonged TPE interval and reperfusion success using ST segment resolution (STR) in patients with STEMI undergoing pPCI.

Methods: In the current study, 218 consecutive patients with STEMI who underwent pPCI were enrolled; after exclusion, 164 patients were included in the study population.

Results: Patients were divided into two groups according to the presence of complete (STR%≥70) or incomplete (STR%<70) STR. Preprocedural corrected TPE (cTPEPRE;116±21 ms vs. 108±21 ms; p=0.027), postprocedural TPE (TPEPOST; 107±16 ms vs. 92±21 ms; p<0.001), and postprocedural cTPE (cTPEPOST; 119±19 ms vs. 102±17 ms; p<0.001) intervals were significantly longer in patients with incomplete STR than in patients with complete STR, whereas there was no statistically significant difference between the two groups in terms of pre- and postprocedural and corrected QT intervals. cTPEPRE and cTPEPOST were found to be independent predictors for incomplete STR.

Conclusion: To our knowledge, this is the first study that evaluated the relationship between TPE interval and no-reflow defined by STR in patients with STEMI who were treated with pPCI.

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Conflict of interest statement

Conflict of interest: None declared.

Figures

Figure 1
Figure 1
Box plot showing the comparison of cTPEPRE (A) and cTPEPOST (B) intervals in patients with complete and incomplete STR
Figure 2
Figure 2
Scatter plot of correlation between STR% and cTPEPRE (a) and cTPEPOST (b) intervals
Figure 3
Figure 3
ROC graphs to detect the best cut-off value of cTPEPRE and cTPEPOST intervals in the prediction of incomplete STR. ROC, receiver operating characteristic; cTPEPRE, preprocedural corrected TPE interval; cTPEPOST, postprocedural corrected TPE interval
See this image and copyright information in PMC

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