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Review
. 2017 Oct-Dec;30(4):283-286.
doi: 10.1590/0102-6720201700040013.

THE ROLE OF THE SLEEVE GASTRECTOMY AND THE MANAGEMENT OF TYPE 2 DIABETES

[Article in English, Portuguese]
Taíse Fuchs  1 , Marcelo Loureiro  1 , Gabriela Heloise Both  2 , Heloise Helena Skraba  2 , Thaís Andrade Costa-Casagrande  1
Affiliations
Review

THE ROLE OF THE SLEEVE GASTRECTOMY AND THE MANAGEMENT OF TYPE 2 DIABETES

[Article in English, Portuguese]
Taíse Fuchs et al. Arq Bras Cir Dig. 2017 Oct-Dec.

Abstract
in English, Portuguese

Background: Currently, bariatric surgery has promoted weight loss and improved glycemic control in obese patients through different techniques, including vertical sleeve gastrectomy.

Aim: Present and update the different vertical sleeve gastrectomy ways of action, both in the treatment of obesity and diabetes, approaching its potential effect on gastrointestinal physiology, as well as the benefits achieved by this manipulation.

Methods: Pubmed database search was used crossing the headings: obesity, type 2 diabetes and sleeve gastrectomy.

Results: Published data have shown that short-term weight loss tends to be higher in patients undergoing vertical sleeve gastrectomy compared to Roux-en-Y gastric bypass. In relation to glycemic control, the procedure demonstrated remission of diabetes in up to 60% after one year of surgery. After three years, however, differences in remission rate between surgical and clinical group was not observed, questioning the durability of the technical in a long-term.

Conclusion: Despite showing good results, both in the weight loss and co-morbidities, conflicting results reinforce the need for more studies to prove the efficiency of the vertical sleeve gastrectomy as well as to understand its action about the molecular mechanisms involved in the disease.

Nos últimos anos a cirurgia bariátrica vem promovendo a perda de peso e melhora do controle glicêmico em pacientes obesos por meio de diversas técnicas, entre elas a gastrectomia vertical.

Apresentar e atualizar as diferentes formas da ação da gastrectomia vertical, tanto no tratamento da obesidade quanto no diabete, abordando seu potencial efeito na fisiologia gastrointestinal, assim como os benefícios obtidos por meio desta manipulação.

Foi realizada revisão de literatura utilizando artigos selecionados na base de dados Pubmed, por meio dos descritores: obesity, type 2 diabetes e sleeve gastrectomy.

Dados publicados demonstraram que a perda de peso em curto prazo tende a ser maior nos pacientes submetidos à gastrectomia vertical quando comparada ao desvio gástrico em Y-de-Roux. Em relação ao controle glicêmico, a técnica apresentou remissão da taxa de diabete em até 60% após um ano. Após três anos, entretanto, diferença na taxa de remissão entre o grupo cirúrgico e clínico não foram evidenciadas, questionando a durabilidade da técnica em longo prazo.

Apesar de apresentar bons resultados no tratamento da obesidade e co-morbidades, resultados conflitantes reforçam a necessidade de mais estudos para demonstrar a eficiência da gastrectomia vertical, assim como para compreender sua ação sobre os mecanismos moleculares envolvidos na doença.

PubMed Disclaimer

Conflict of interest statement

Conflict of interest: none

References

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