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Review
. 2018 Jan;105(2):e19-e30.
doi: 10.1002/bjs.10790.

Role of micro-RNAs in breast cancer surgery

P McAnena  1 , A Lowery  1 , M J Kerin  1
Affiliations
Review

Role of micro-RNAs in breast cancer surgery

P McAnena et al. Br J Surg. 2018 Jan.

Abstract

Background: The management of breast cancer has changed dramatically in the molecular era. Micro-RNAs can contribute to multiple facets of cancer surgery.

Methods: This narrative review, based on years of research on the role of micro-RNAs, focused on the potential of these small, robust RNAs to influence all aspects of breast cancer surgery.

Results: Micro-RNAs have a potential role as biomarkers in the diagnosis, prognosis and evaluation of response to therapy in breast cancer. They may also contribute to future therapeutic strategies.

Conclusion: The molecular era has changed understanding of cancer. Micro-RNAs have the potential for use in personalized cancer strategies.

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