Obesity is not just elevated adiposity, it is also a state of metabolic perturbation
- PMID: 29342588
- DOI: 10.1017/S0140525X16001552
Obesity is not just elevated adiposity, it is also a state of metabolic perturbation
Abstract
Nettle et al. miss the crucial difference between adaptive models of storing energy and explanations for the pathological metabolic state of obesity. I suggest that the association of food insecurity with obesity in women from industrialized settings is most likely due to reverse causation: Poverty reduces agency to resist obesogenic foods, and this scenario is compounded by perturbations of insulin metabolism stemming from high adiposity and lipogenic diets.
Comment on
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