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Comment
. 2018 Jan 16;48(1):1-3.
doi: 10.1016/j.immuni.2018.01.003.

Gasdermin D Flashes an Exit Signal for IL-1

Teneema Kuriakose  1 , Thirumala-Devi Kanneganti  2
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Comment

Gasdermin D Flashes an Exit Signal for IL-1

Teneema Kuriakose et al. Immunity. .
Free article

Abstract

The IL-1 family of cytokines follows an unconventional pathway of secretion mostly associated with inflammatory cell death. In this issue of Immunity, (Evavold et al., 2017) report gasdermin D pores as channels for active IL-1 release in live phagocytic cells.

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