New Job for NK Cells: Architects of the Tumor Microenvironment
- PMID: 29343443
- DOI: 10.1016/j.immuni.2018.01.001
New Job for NK Cells: Architects of the Tumor Microenvironment
Abstract
NK cells control tumor growth directly through targeted cytotoxic granule release or cytokine secretion and indirectly by orchestrating anti-tumor immune responses. In this issue of Immunity, Glasner et al. (2018) now reveal a new role for NK cells in preventing metastatic spread through controlling tumor architecture.
Copyright © 2018. Published by Elsevier Inc.
Comment on
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NKp46 Receptor-Mediated Interferon-γ Production by Natural Killer Cells Increases Fibronectin 1 to Alter Tumor Architecture and Control Metastasis.Immunity. 2018 Jan 16;48(1):107-119.e4. doi: 10.1016/j.immuni.2017.12.007. Epub 2018 Jan 9. Immunity. 2018. PMID: 29329948
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