Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2017 Dec 31;7(2):115-117.
doi: 10.14581/jer.17018. eCollection 2017 Dec.

Aphasic Status Epilepticus Associated with Uremia

Min-Surk Kye  1 , Jung-Ju Lee  1 , Byung-Kun Kim  1 , Ohyun Kwon  1 , Jong Moo Park  1 , Kyusik Kang  1 , Woong-Woo Lee  1
Affiliations
Case Reports

Aphasic Status Epilepticus Associated with Uremia

Min-Surk Kye et al. J Epilepsy Res. .

Abstract

Aphasic status epilepticus (ASE) is a rare disorder characterized by recurrent aphasia without impairment of other cognitive functions. A 76-year-old woman with chronic kidney disease developed ASE after neglecting peritoneal dialysis. Magnetic resonance imaging failed to demonstrate an appropriate lesion. Electroencephalography demonstrated ictal discharges in the left frontotemporal leads. ASE disappeared after intravenous valproic acid and correction of uremia. This is the first case report of ASE in a patient with acute aggravation of uremia.

Keywords: Aphasic status epilepticus; Cognitive function; Uremia.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Brain magnetic resonance imaging and angiogram. Fluid-attenuated inversion recovery (FLAIR) (A) and diffusion weighted imaging (B) revealed no abnormality. No significant stenosis was observed on magnetic resonance angiogram (C).
Figure 2
Figure 2
Electroencephalography obtained during the aphasic period. (A) Beginning; (B) 20 seconds after seizure onset; (C) 40 seconds after seizure onset; and (D) 60 seconds after seizure onset. Rhythmic theta activity initiated from the left frontotemporal leads (black arrow) and evolved to high amplitude rhythmic delta activity. Later, it spread to the right frontotemporal area.
See this image and copyright information in PMC

References

    1. Ericson EJ, Gerard EE, Macken MP, Schuele SU. Aphasic status epilepticus: electroclinical correlation. Epilepsia. 2011;52:1452–8. - PubMed
    1. Toledo M, Munuera J, Sueiras M, Rovira R, Alvarez-Sabín J, Rovira A. MRI findings in aphasic status epilepticus. Epilepsia. 2008;49:1465–9. - PubMed
    1. Chung PW, Seo DW, Kwon JC, Kim H, Na DL. Nonconvulsive status epilepticus presenting as a subacute progressive aphasia. Seizure. 2002;11:449–54. - PubMed
    1. Manford M, Fuller GN, Wade JP. “Silent diabetes”: non-ketotic hyperglycaemia presenting as aphasic status epilepticus. J Neurol Neurosurg Psychiatry. 1995;59:99–100. - PMC - PubMed
    1. Kim J, Lee S, Lee JJ, et al. Aphasic seizure as a manifestation of non-ketotic hyperglycemia. J Korean Neurol Assoc. 2012;30:309–11.

Publication types

LinkOut - more resources