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Case Reports
. 2018 Mar 1;154(3):362-363.
doi: 10.1001/jamadermatol.2017.5463.

Variable Response to Naltrexone in Patients With Hailey-Hailey Disease

Severine Cao  1 , Evelyn Lilly  1   2 , Steven T Chen  1   2   3
Affiliations
Case Reports

Variable Response to Naltrexone in Patients With Hailey-Hailey Disease

Severine Cao et al. JAMA Dermatol. .

Abstract

This case series presents 3 cases of patients with Hailey-Hailey disease demonstrating varying responses to naltrexone.

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Conflict of interest statement

Conflict of Interest Disclosures: None reported.

Figures

Figure.
Figure.. Clinical Response to Naltrexone 12.5 mg Nightly
Clinical photographs show (A) the right axilla of a patient at baseline with large macerated plaques with superficial erosions, and (B) the patient’s right axilla after 2 months of treatment with naltrexone 12.5 mg nightly demonstrating complete resolution.
See this image and copyright information in PMC

References

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    1. Ibrahim O, Hogan SR, Vij A, Fernandez AP. Low-dose naltrexone treatment of familial benign pemphigus (Hailey-Hailey disease). JAMA Dermatol. 2017;153(10):1015-1017. - PMC - PubMed
    1. Albers LN, Arbiser JL, Feldman RJ. Treatment of Hailey-Hailey disease with low-dose naltrexone. JAMA Dermatol. 2017;153(10):1018-1020. - PMC - PubMed