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Practice Guideline
. 2018 May 1;36(13):1343-1373.
doi: 10.1200/JCO.2017.76.6394. Epub 2018 Jan 18.

Treatment of Malignant Pleural Mesothelioma: American Society of Clinical Oncology Clinical Practice Guideline

Hedy L Kindler  1 , Nofisat Ismaila  1 , Samuel G Armato 3rd  1 , Raphael Bueno  1 , Mary Hesdorffer  1 , Thierry Jahan  1 , Clyde Michael Jones  1 , Markku Miettinen  1 , Harvey Pass  1 , Andreas Rimner  1 , Valerie Rusch  1 , Daniel Sterman  1 , Anish Thomas  1 , Raffit Hassan  1
Affiliations
Practice Guideline

Treatment of Malignant Pleural Mesothelioma: American Society of Clinical Oncology Clinical Practice Guideline

Hedy L Kindler et al. J Clin Oncol. .

Abstract

Purpose To provide evidence-based recommendations to practicing physicians and others on the management of malignant pleural mesothelioma. Methods ASCO convened an Expert Panel of medical oncology, thoracic surgery, radiation oncology, pulmonary, pathology, imaging, and advocacy experts to conduct a literature search, which included systematic reviews, meta-analyses, randomized controlled trials, and prospective and retrospective comparative observational studies published from 1990 through 2017. Outcomes of interest included survival, disease-free or recurrence-free survival, and quality of life. Expert Panel members used available evidence and informal consensus to develop evidence-based guideline recommendations. Results The literature search identified 222 relevant studies to inform the evidence base for this guideline. Recommendations Evidence-based recommendations were developed for diagnosis, staging, chemotherapy, surgical cytoreduction, radiation therapy, and multimodality therapy in patients with malignant pleural mesothelioma. Additional information is available at www.asco.org/thoracic-cancer-guidelines and www.asco.org/guidelineswiki .

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Conflict of interest statement

AUTHORS’ DISCLOSURES OF POTENTIAL CONFLICTS OF INTEREST

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