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Comment
. 2018 Jan 17;97(2):253-255.
doi: 10.1016/j.neuron.2018.01.002.

The THIK and Thin of Microglia Dynamics

Jennifer Shih  1 , Chris G Dulla  2
Affiliations
Free article
Comment

The THIK and Thin of Microglia Dynamics

Jennifer Shih et al. Neuron. .
Free article

Abstract

Madry et al. (2018) show that the two-pore potassium channel THIK-1 is tonically active in microglia and promotes microglial ramification and surveillance of the brain parenchyma. Interestingly, THIK-1 is not essential to damage-induced outgrowth of microglial processes but is critical to microglial IL-1β release.

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