CART Targeting of Solid Tumors: More Pieces to the Puzzle
- PMID: 29348296
- DOI: 10.1158/1078-0432.CCR-17-3432
CART Targeting of Solid Tumors: More Pieces to the Puzzle
Abstract
Chimeric antigen receptor-modified T (CART)-cell-based targeting of solid tumors remains a considerable and worthwhile challenge in the field of immunotherapy. The role of chemotherapy to target stroma and enhance chimeric antigen receptor (CAR) cell antitumor function, expansion, and persistence is still unresolved. Clin Cancer Res; 24(6); 1246-7. ©2018 AACRSee related article by Guo et al., p. 1277.
©2018 American Association for Cancer Research.
Comment on
-
Phase I Study of Chimeric Antigen Receptor-Modified T Cells in Patients with EGFR-Positive Advanced Biliary Tract Cancers.Clin Cancer Res. 2018 Mar 15;24(6):1277-1286. doi: 10.1158/1078-0432.CCR-17-0432. Epub 2017 Nov 14. Clin Cancer Res. 2018. PMID: 29138340 Clinical Trial.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Research Materials
Miscellaneous
