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Comment
. 2018 Mar 15;24(6):1246-1247.
doi: 10.1158/1078-0432.CCR-17-3432. Epub 2018 Jan 18.

CART Targeting of Solid Tumors: More Pieces to the Puzzle

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Comment

CART Targeting of Solid Tumors: More Pieces to the Puzzle

Michael Kalos. Clin Cancer Res. .

Abstract

Chimeric antigen receptor-modified T (CART)-cell-based targeting of solid tumors remains a considerable and worthwhile challenge in the field of immunotherapy. The role of chemotherapy to target stroma and enhance chimeric antigen receptor (CAR) cell antitumor function, expansion, and persistence is still unresolved. Clin Cancer Res; 24(6); 1246-7. ©2018 AACRSee related article by Guo et al., p. 1277.

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