Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2018 Feb;24(2):393-394.
doi: 10.3201/eid2402.171411.

Cronobacter sakazakii Infection from Expressed Breast Milk, Australia

Case Reports

Cronobacter sakazakii Infection from Expressed Breast Milk, Australia

Rowena McMullan et al. Emerg Infect Dis. 2018 Feb.

Abstract

Cronobacter sakazakii neonatal infections are often epidemiologically linked to the consumption of contaminated powdered infant formula. We describe a case resulting from consumption of contaminated expressed breast milk, as confirmed by whole-genome sequencing. This case highlights potential risks associated with storage and acquisition of expressed breast milk.

Keywords: Australia; Cronobacter sakazakii; bacteria; bacterial infections; expressed breast milk; meningitis/encephalitis; neonates.

PubMed Disclaimer

Figures

Figure
Figure
Maximum-likelihood phylogeny of Cronobacter isolates cultured from the blood of an infant (Ck0001) and the mother’s expressed breast milk (Ck0002) with C. sakazakii Sp291 as reference. Shaded circle highlights the clustering of sequence type 4 isolates. Scale bar indicates nucleotide substitutions per site. Methods for culturing isolates described in Technical Appendix. ST, sequence type.

References

    1. Kalyantanda G, Shumyak L, Archibald LK. Cronobacter species contamination of powdered infant formula and the implications for neonatal health. Front Pediatr. 2015;3:56. 10.3389/fped.2015.00056 - DOI - PMC - PubMed
    1. Bowen A, Wiesenfeld HC, Kloesz JL, Pasculle AW, Nowalk AJ, Brink L, et al. Notes from the field: Cronobacter sakazakii infection associated with feeding extrinsically contaminated expressed human milk to a premature infant—Pennsylvania, 2016. MMWR Morb Mortal Wkly Rep. 2017;66:761–2. 10.15585/mmwr.mm6628a5 - DOI - PMC - PubMed
    1. Hurrell E, Kucerova E, Loughlin M, Caubilla-Barron J, Hilton A, Armstrong R, et al. Neonatal enteral feeding tubes as loci for colonisation by members of the Enterobacteriaceae. BMC Infect Dis. 2009;9:146. 10.1186/1471-2334-9-146 - DOI - PMC - PubMed
    1. Lenati RF, O’Connor DL, Hébert KC, Farber JM, Pagotto FJ. Growth and survival of Enterobacter sakazakii in human breast milk with and without fortifiers as compared to powdered infant formula. Int J Food Microbiol. 2008;122:171–9. 10.1016/j.ijfoodmicro.2007.11.084 - DOI - PubMed
    1. Centers for Disease Control and Prevention. How to your breast pump kit clean: the essentials [cited 2017 Aug 1]. https://www.cdc.gov/healthywater/hygiene/healthychildcare/infantfeeding/...

LinkOut - more resources