Clip ligation for ruptured intracranial aneurysm in a child with Loeys-Dietz syndrome: case report

Abstract

The authors present the case of a pediatric patient with Loeys-Dietz syndrome (LDS) who underwent craniotomy for clip ligation of a ruptured intracranial aneurysm. To the authors' knowledge, this is the youngest reported patient with LDS who has been treated for a ruptured intracranial aneurysm. The patient presented with aneurysmal subarachnoid hemorrhage even though the results of surveillance screening were negative, and the aneurysm arose from the wall of the parent artery away from an arterial branch point. She was treated with open clip ligation and recovered well. The authors review the other reported cases of treated intracranial aneurysms in patients with LDS.

Keywords: CTA = CT angiography; ICA = internal carotid artery; IVH = intraventricular hemorrhage; LDS = Loeys-Dietz syndrome; Loeys-Dietz syndrome; MRA = MR angiography; PICA = posterior inferior cerebellar artery; SAH = subarachnoid hemorrhage; craniotomy; intracranial aneurysm; subarachnoid hemorrhage; vascular disorders.