REV-ERB Agonists Block Autophagy in Cancer Cells
- PMID: 29352049
- DOI: 10.1158/2159-8290.CD-RW2018-011
REV-ERB Agonists Block Autophagy in Cancer Cells
Abstract
Disruption of the circadian clock components reduces cancer cell viability in vitro and in vivo.
©2018 American Association for Cancer Research.
Comment on
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Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence.Nature. 2018 Jan 18;553(7688):351-355. doi: 10.1038/nature25170. Epub 2018 Jan 10. Nature. 2018. PMID: 29320480 Free PMC article.
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