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. 1986 Jan;72(1):77-9.
doi: 10.1007/BF00278822.

Retro- and prospective evaluation of dynamics of some mutational events

N P Bochkov, S D Grigorian, I N Lunga, I V Nikolaeva, V M Prussakov, M V Tikhopoy

Retro- and prospective evaluation of dynamics of some mutational events

N P Bochkov et al. Hum Genet. 1986 Jan.

Abstract

The dynamics of some mutational events were studied in a Siberian town with a chemical industry. Retro- and prospective evaluations of the frequency of spontaneous abortions, multiple congenital malformations, and Down syndrome were carried out. Mutational components of these endpoints were summarized and provisionally termed "units of mutational events" (UME). The results show that the frequencies of UME have not changed in 14 years.

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