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. 2018 May 11;4(5):656-659.
doi: 10.1021/acsinfecdis.8b00004. Epub 2018 Jan 22.

Potential Mechanisms for Enhanced Zika Epidemic and Disease

Hongjie Xia, Xuping Xie, Chao Shan, Pei-Yong Shi

Potential Mechanisms for Enhanced Zika Epidemic and Disease

Hongjie Xia et al. ACS Infect Dis. .

Abstract

A number of mechanisms have driven the explosive epidemics and severe diseases of Zika virus since 2007. Here, we comment on how herd immunity, heterologous flavivirus preimmunity, and viral mutations could enhance the epidemic potential and disease severity of Zika virus in humans.

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