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Review
. 2018 Jan 22;376(1):5.
doi: 10.1007/s41061-018-0184-5.

Analysis of US FDA-Approved Drugs Containing Sulfur Atoms

Kevin A Scott  1   2 , Jon T Njardarson  3
Affiliations
Review

Analysis of US FDA-Approved Drugs Containing Sulfur Atoms

Kevin A Scott et al. Top Curr Chem (Cham). .

Abstract

In this review, we discuss all sulfur-containing FDA-approved drugs and their structures. The second section of the review is dedicated to structural analysis and is divided into 14 subsections, each focusing on one type of sulfur-containing moiety. A concise graphical representation of each class features drugs that are organized on the basis of structural similarity, evolutionary relevance, and medical indication. This review offers a unique and comprehensive overview of the structural features of all sulfur-containing FDA-approved drugs to date.

Keywords: Sulfate; Sulfonamide; Sulfone; Sulfoxide; Sulfur heterocycle; Thioether.

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