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. 2018 Jul;32(7):3349-3356.
doi: 10.1007/s00464-018-6055-x. Epub 2018 Jan 23.

Use of a novel technique to manage gastrointestinal leaks with endoluminal negative pressure: a single institution experience

Marissa A Mencio  1 , Estrellita Ontiveros  1 , James S Burdick  2 , Steven G Leeds  3
Affiliations

Use of a novel technique to manage gastrointestinal leaks with endoluminal negative pressure: a single institution experience

Marissa A Mencio et al. Surg Endosc. 2018 Jul.

Abstract

Background: Perforations and anastomotic leaks of the gastrointestinal tract are severe complications, which carry high morbidity and mortality and management of these is a multi-disciplinary challenge. The use of endoluminal vacuum (EVAC) therapy has recently proven to be a useful technique to manage these complications. We report our institution's experience with this novel technique in the chest, abdomen, and pelvis.

Methods: This is a retrospective review of an IRB approved registry of all EVAC therapy patients from July 2013 to December 2016. A total of 55 patients were examined and 49 patients were eligible for inclusion: 15 esophageal, 21 gastric, 3 small bowel, and 10 colorectal defects. The primary endpoint was closure rate of the GI tract defect with EVAC therapy.

Results: Fifteen (100%) esophageal defects closed with EVAC therapy. Mean duration of therapy was 27 days consisting of an average of 6 endosponge changes every 4.8 days. Eighteen (86%) gastric defects closed with EVAC therapy. Mean duration of therapy was 38 days with a mean of 9 endosponge changes every 5.3 days. Three (100%) small bowel defects closed with EVAC therapy. Mean duration of therapy was 13.7 days with a mean of 2.7 endosponge changes every 4.4 days. Six (60%) colorectal defects closed with EVAC therapy. Mean duration of therapy was 23.2 days, consisting of a mean of 6 endosponge changes every 4.0 days. There were two deaths, which were not directly related to EVAC therapy and occurred outside the measured 30-day mortality.

Conclusion: Our experience demonstrates that EVAC therapy is feasible and effective for the management of gastrointestinal perforations/leaks throughout the GI tract and can be considered as a safe alternative to surgical intervention in select cases.

Keywords: Anastomotic leak; Bariatric complication; Endoluminal vacuum therapy; Esophageal perforation; Gastrointestinal leaks; Sleeve leak.

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