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. 2018 Feb 23;81(2):423-446.
doi: 10.1021/acs.jnatprod.7b00921. Epub 2018 Jan 24.

Natural Products Containing a Nitrogen-Sulfur Bond

Janusz J Petkowski  1 , William Bains  2 , Sara Seager  1   3
Affiliations

Natural Products Containing a Nitrogen-Sulfur Bond

Janusz J Petkowski et al. J Nat Prod. .

Abstract

Only about 100 natural products are known to contain a nitrogen-sulfur (N-S) bond. This review thoroughly categorizes N-S bond-containing compounds by structural class. Information on biological source, biological activity, and biosynthesis is included, if known. We also review the role of N-S bond functional groups as post-translational modifications of amino acids in proteins and peptides, emphasizing their role in the metabolism of the cell.

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