Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1979 Nov;76(11):5539-43.
doi: 10.1073/pnas.76.11.5539.

Covalent association of protein with replicative form DNA of parvovirus H-1

D Revie, B Y Tseng, R H Grafstrom, M Goulian

Covalent association of protein with replicative form DNA of parvovirus H-1

D Revie et al. Proc Natl Acad Sci U S A. 1979 Nov.

Abstract

The double-stranded replicative form (RF) DNA of the autonomous parvovirus H-1 can be isolated from infected cells in a covalent complex with protein. The protein is present on most or all of the RF DNA, including actively replicating molecules, and is associated with the 5'-terminal endonuclease Hae III fragments of both the viral and complementary strands of RF. The size of the protein is estimated to be 60,000-70,000 daltons from its effect on buoyant density of DNA. DNA with covalently bound protein has not been found in H-1 virions.

PubMed Disclaimer

References

    1. J Virol. 1978 Jan;25(1):215-23 - PubMed
    1. Virology. 1978 Aug;89(1):112-8 - PubMed
    1. Virology. 1978 Feb;84(2):434-42 - PubMed
    1. Virology. 1976 Oct 1;74(1):57-63 - PubMed
    1. Nature. 1976 Sep 9;263(5573):106-9 - PubMed

Publication types

LinkOut - more resources