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. 2017 Dec 30;11(4):463-468.
eCollection 2017 Dec.

Brucellosis in Patients with Crimean-Congo Hemorrhagic Fever

Fazilet Duygu  1 , Tugba Sari  1 , Turan Kaya  2 , Nermin Bulut  3
Affiliations

Brucellosis in Patients with Crimean-Congo Hemorrhagic Fever

Fazilet Duygu et al. J Arthropod Borne Dis. .

Abstract

Background: Crimean-Congo hemorrhagic fever (CCHF) is a fatal zoonotic viral disease caused by infection with a tick-borne virus of the genus Nairovirus. In this study, we investigated the incidence of brucellosis in patients diagnosed with CCHF.

Methods: Overall, 169 patients hospitalized with an initial diagnosis of CCHF were included in 2011 in Tokat/Turkey. Immunoglobulin M (IgM) antibodies and/or PCR results were used in the laboratory diagnosis of CCHF, while plate and standard tube agglutination (STA) tests were used to diagnose brucellosis.

Results: Overall, 120 patients (79%) with positive PCR tests were diagnosed with CCHF. Five (4.16%) were also diagnosed with brucellosis based on the positive plate and STA test results. Four patients (2.36%) had negative CCHF PCR and positive STA test results.

Conclusion: Brucellosis and CCHF can mimic each other and that all patients with CCHF or brucellosis should be screened for both conditions.

Keywords: Brucellosis; Crimean-Congo hemorrhagic fever; Haemorrhagic fever; Zoonosis.

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