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. 1985 Nov;39(3):395-7.
doi: 10.1254/jjp.39.395.

State-dependent effects of beta-endorphin on core temperature in stressed and non-stressed rats

M Tanaka, A Tsuda, Y Ida, I Ushijima, S Tsujimaru, N Nagasaki
Free article

State-dependent effects of beta-endorphin on core temperature in stressed and non-stressed rats

M Tanaka et al. Jpn J Pharmacol. 1985 Nov.
Free article

Abstract

beta-Endorphin, gamma-endorphin, delta-endorphin and morphine injected i.c.v. caused hyperthermia in non-stressed rats; however, the same dose of beta-endorphin and morphine caused hypothermia in stressed animals. These effects of beta-endorphin were antagonized by naloxone. The results suggest that effects of beta-endorphin are different depending on the animal's state and that these effects are mediated via opioid receptors.

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