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. 2018 Mar;20(3):462-468.
doi: 10.1111/jch.13200. Epub 2018 Jan 25.

Relationship between brachial-ankle pulse wave velocity and invasively measured aortic pulse pressure

Jeehoon Kang  1   2 , Hack-Lyoung Kim  1 , Woo-Hyun Lim  1 , Jae-Bin Seo  1 , Joo-Hee Zo  1 , Myung-A Kim  1 , Sang-Hyun Kim  1
Affiliations

Relationship between brachial-ankle pulse wave velocity and invasively measured aortic pulse pressure

Jeehoon Kang et al. J Clin Hypertens (Greenwich). 2018 Mar.

Abstract

Although brachial-ankle pulse wave velocity (baPWV) has been widely used as an index of arterial stiffness, no consensus exists about whether baPWV can reflect central aortic stiffness. The authors investigated the association between baPWV and invasively measured aortic pulse pressure (APP) in a total of 109 consecutive patients (mean age, 62.3 ± 11.3 years; 67.9% men). Most patients (91%) had obstructive coronary artery disease, and mean baPWV and APP values were 1535 ± 303 cm/s and 66.8 ± 22.5 mm Hg, respectively. In univariate analysis, there was a significant linear correlation between baPWV and APP (r = .635, P < .001). The correlation between baPWV and APP remained significant even after controlling for potential confounders (β = 0.574, P < .001; R2 = .469). Arterial stiffness measured by baPWV showed a strong positive correlation with invasively measured APP, independent of clinical confounders. Therefore, baPWV can be a good marker of central aortic stiffness.

Keywords: aortic pulse pressure; aortic stiffness; correlation; pulse wave velocity.

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Figures

Figure 1
Figure 1
Linear correlation (A) between brachial‐ankle pulse wave velocity and invasively measured aortic pulse pressure, and (B) between brachial‐ankle pulse wave velocity and brachial pulse pressure
See this image and copyright information in PMC

Comment in

References

    1. Dart AM, Kingwell BA. Pulse pressure––a review of mechanisms and clinical relevance. J Am Coll Cardiol. 2001;37:975‐984. - PubMed
    1. Safar ME, Levy BI, Struijker‐Boudier H. Current perspectives on arterial stiffness and pulse pressure in hypertension and cardiovascular diseases. Circulation. 2003;107:2864‐2869. - PubMed
    1. Vlachopoulos C, Aznaouridis K, Stefanadis C. Prediction of cardiovascular events and all‐cause mortality with arterial stiffness: a systematic review and meta‐analysis. J Am Coll Cardiol. 2010;55:1318‐1327. - PubMed
    1. Nichols WW, Denardo SJ, Wilkinson IB, McEniery CM, Cockcroft J, O'Rourke MF. Effects of arterial stiffness, pulse wave velocity, and wave reflections on the central aortic pressure waveform. J Clin Hypertens (Greenwich). 2008;10:295‐303. - PMC - PubMed
    1. Brown DW, Giles WH, Croft JB. Left ventricular hypertrophy as a predictor of coronary heart disease mortality and the effect of hypertension. Am Heart J. 2000;140:848‐856. - PubMed

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