Dimerization Is Critical for the Functions of Wild-type and Mutant KRAS
- PMID: 29374019
- DOI: 10.1158/2159-8290.CD-RW2018-013
Dimerization Is Critical for the Functions of Wild-type and Mutant KRAS
Abstract
Wild-type KRAS increases survival and resistance to MEK inhibitors in KRAS-mutant lung cancer cells.
©2018 American Association for Cancer Research.
Comment on
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KRAS Dimerization Impacts MEK Inhibitor Sensitivity and Oncogenic Activity of Mutant KRAS.Cell. 2018 Feb 8;172(4):857-868.e15. doi: 10.1016/j.cell.2017.12.020. Epub 2018 Jan 11. Cell. 2018. PMID: 29336889
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