Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2015 Aug 19;1(2):173-184.
doi: 10.3390/jof1020173.

The Dermatologist's Approach to Onychomycosis

Affiliations
Review

The Dermatologist's Approach to Onychomycosis

Jenna N Queller et al. J Fungi (Basel). .

Abstract

Onychomycosis is a fungal infection of the toenails or fingernails that can involve any component of the nail unit, including the matrix, bed, and plate. It is a common disorder that may be a reservoir for infection resulting in significant medical problems. Moreover, onychomycosis can have a substantial influence on one's quality of life. An understanding of the disorder and updated management is important for all health care professionals. Aside from reducing quality of life, sequelae of the disease may include pain and disfigurement, possibly leading to more serious physical and occupational limitations. Dermatologists, Podiatrists, and other clinicians who treat onychomycosis are now entering a new era when considering treatment options-topical modalities are proving more effective than those of the past. The once sought after concept of viable, effective, well-tolerated, and still easy-to-use monotherapy alternatives to oral therapy treatments for onychomycosis is now within reach given recent study data. In addition, these therapies may also find a role in combination and maintenance therapy; in order to treat the entire disease the practitioner needs to optimize these topical agents as sustained therapy after initial clearance to reduce recurrence or re-infection given the nature of the disease.

Keywords: maintenance; onycholysis; onychomycosis; recurrence; subungual hyperkeratosis.

PubMed Disclaimer

Conflict of interest statement

Dr. Queller has no conflicts of interest. Dr. Bhatia is an advisor, consultant, investigator, and speaker for Anacor, Merz, Sandoz, and Valeant.

Similar articles

Cited by

References

    1. Scher R.K., Daniel C.R., III . Nails: Therapy, Diagnosis, Surgery. 3rd ed. Elsevier Saunders; Philadelphia, PA, USA: 2005. pp. 127–170.
    1. Crissey J.T. Common dermatophyte infections. A simple diagnostic test and current management. Postgrad. Med. 1998;103:191–192, 197–200, 205. doi: 10.3810/pgm.1998.02.359. - DOI - PubMed
    1. Kemna M.E., Elewski B.E. A U.S. epidemiologic survey of superficial fungal diseases. J. Am. Acad. Dermatol. 1996;35:539–542. doi: 10.1016/S0190-9622(96)90675-1. - DOI - PubMed
    1. Elewski B.E. Onychomycosis. Treatment, quality of life, and economic issues. Am. J. Clin. Dermatol. 2000;1:19–26. doi: 10.2165/00128071-200001010-00002. - DOI - PubMed
    1. Elewski B.E. Onychomycosis: Pathogenesis, diagnosis, and management. Clin. Microbiol. Rev. 1998;11:415–429. doi: 10.2165/00128071-200001010-00002. - DOI - PMC - PubMed

LinkOut - more resources