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. 2018 Jan 29;22(1):24.
doi: 10.1186/s13054-018-1945-9.

Back-to-back comparison of penKID with NephroCheck® to predict acute kidney injury at admission in intensive care unit: a brief report

Collaborators, Affiliations

Back-to-back comparison of penKID with NephroCheck® to predict acute kidney injury at admission in intensive care unit: a brief report

Etienne Gayat et al. Crit Care. .
No abstract available

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Conflict of interest statement

Ethics approval and consent to participate

The study was conducted in France and Belgium in accordance with Good Clinical Practice (Declaration of Helsinki 2002) and Ethical Committee approvals (Comité de Protection des Personnes—Ile de France IV, IRB number 00003835 and Commission d’éthique biomédicale hospitalo-facultaire de l’hôpital de Louvain, IRB number B403201213352). It is registered on ClinicalTrials.gov (NCT01367093). Patients were included from August 2011 to June 2013.

Consent for publication

Not applicable.

Competing interests

Etienne Gayat received a research grant from sphingotec, consultancy fees from Magnisense, Roche Diagnostics. Alexandre Mebazaa received speaker’s honoraria from Abbott, Novartis, Orion, Roche et Servier and a fee as a member of the advisory board and/or Steering Committee from Cardiorentis, Adrenomed, MyCartis, Neurotronik, and sphingotec. All other co-authors have no conflicts of interest related to the present manuscript.

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Figures

Fig. 1
Fig. 1
Boxplot of penKid (grey) and NephroCheck (white) levels according to severity of AKI as defined by KDIGO (left panel) and respective ROC curves predicting AKI (right panel)

References

    1. Darmon M, Ostermann M, Cerda J3, Dimopoulos MA, Forni L, Hoste E, Legrand M, Lerolle N, Rondeau E, Schneider A, Souweine B, Schetz M. Diagnostic work-up and specific causes of acute kidney injury. Intensive Care Med. 2017;43(6):829–40. 10.1007/s00134-017-4799-8. Epub 2017 Apr 25. - PubMed
    1. Bihorac A, Chawla LS, Shaw AD, Al-Khafaji A, Davison DL, Demuth GE, Fitzgerald R, Gong MN, Graham DD, Gunnerson K, Heung M, Jortani S, Kleerup E, Koyner JL, Krell K, Letourneau J, Lissauer M, Miner J, Nguyen HB, Ortega LM, Self WH, Sellman R, Shi J, Straseski J, Szalados JE, Wilber ST, Walker MG, Wilson J, Wunderink R, Zimmerman J, Kellum JA. Validation of cell-cycle arrest biomarkers for acute kidney injury using clinical adjudication. Am J Respir Crit Care Med. 2014;189:932–9. doi: 10.1164/rccm.201401-0077OC. - DOI - PubMed
    1. Marino R, Struck J, Hartmann O, Maisel AS, Rehfeldt M, Magrini L, Melander O, Bergmann A, Di Somma S. Diagnostic and short-term prognostic utility of plasma pro-enkephalin (pro-ENK) for acute kidney injury in patients admitted with sepsis in the emergency department. J Nephrol. 2015;28:717–24. doi: 10.1007/s40620-014-0163-z. - DOI - PubMed
    1. Ng LL, Squire IB, Jones DJ, Cao TH, Chan DC, Sandhu JK, Quinn PA, Davies JE, Struck J, Hartmann O, Bergmann A, Mebazaa A, Gayat E, Arrigo M, Akiyama E, Sabti Z, Lohrmann J, Twerenbold R, Herrmann T, Schumacher C, Kozhuharov N, Mueller C, Network G. Proenkephalin, renal dysfunction, and prognosis in patients with acute heart failure: a GREAT Network study. J Am Coll Cardiol. 2017;69:56–69. doi: 10.1016/j.jacc.2016.10.038. - DOI - PubMed
    1. Sezen SF, Kenigs VA, Kapusta DR. Renal excretory responses produced by the delta opioid agonist, BW373U86, in conscious rats. J Pharmacol Exp Ther. 1998;287:238–45. - PubMed

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