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Review
. 2018 Jan;26(1):64-70.
doi: 10.1016/j.jsps.2017.10.012. Epub 2017 Oct 25.

Applications of nanoparticle systems in drug delivery technology

Syed A A Rizvi  1 , Ayman M Saleh  2
Affiliations
Review

Applications of nanoparticle systems in drug delivery technology

Syed A A Rizvi et al. Saudi Pharm J. 2018 Jan.

Abstract

The development of nanoparticle-based drug formulations has yielded the opportunities to address and treat challenging diseases. Nanoparticles vary in size but are generally ranging from 100 to 500 nm. Through the manipulation of size, surface characteristics and material used, the nanoparticles can be developed into smart systems, encasing therapeutic and imaging agents as well as bearing stealth property. Further, these systems can deliver drug to specific tissues and provide controlled release therapy. This targeted and sustained drug delivery decreases the drug related toxicity and increase patient's compliance with less frequent dosing. Nanotechnology has proven beneficial in the treatment of cancer, AIDS and many other disease, also providing advancement in diagnostic testing.

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Figures

Fig. 1
Fig. 1
Representation of a smart multifunctional drug loaded nanoparticle, decorated with various moieties for targeting, imaging and stealth properties.
See this image and copyright information in PMC

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