[Proof of the effectiveness of a clotrimazole cream paste in acne vulgaris]
- PMID: 2938349
[Proof of the effectiveness of a clotrimazole cream paste in acne vulgaris]
Abstract
The efficacy of Clotrimazol cream paste containing a penetration enhancer in the treatment of acne vulgaris was objectified by investigating the sebum composition. Following treatment over three and six weeks, the ratio of triglyceride to free fatty acid significantly increased, which indicated an effective reduction of the lipase activity of Propionibacterium acnes within the sebaceous follicle.
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