Review
doi: 10.1051/medsci/20183401017.
Epub 2018 Jan 31.
[EBV/KSHV co-infection: an effective partnership]
[Article in
French]
Affiliations
- PMID: 29384100
- DOI: 10.1051/medsci/20183401017
Item in Clipboard
Review
[EBV/KSHV co-infection: an effective partnership]
[Article in
French]
Med Sci (Paris).
2018 Jan.
Free article
Abstract
Kaposi's sarcoma human herpesvirus (KSHV) is the etiologic agent of primary effusion lymphoma (PEL) in which Epstein-Barr virus (EBV) is also very often present. By using a humanized mouse model, Pr. Münz's team has been able to demonstrate that EBV/KSHV co-infection increases KSHV persistence and cell transformation through the stimulation of EBV replication. This is the first model of PEL in small animals, opening up exciting prospects for future studies on this unique lymphoma.
© 2018 médecine/sciences – Inserm.
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