Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2018 Feb;97(5):e9758.
doi: 10.1097/MD.0000000000009758.

Spontaneous cerebrospinal fluid rhinorrhea: A case report and analysis

Guang Yong Chen  1 , Long Ma, Mei Ling Xu, Jin Nan Zhang, Zhi Dong He, Cheng Yan He, Cong Hai Zhao, Chao Fu, Miao Li, Yu Fei Gao
Affiliations
Case Reports

Spontaneous cerebrospinal fluid rhinorrhea: A case report and analysis

Guang Yong Chen et al. Medicine (Baltimore). 2018 Feb.

Erratum in

Abstract

Introduction: Spontaneous cerebrospinal fluid leakage is usually caused by developmental abnormalities and is rare, accounting for approximately 5% of the cases of cerebrospinal fluid (CSF) leakage. To the best of our knowledge, clival dysplasia-caused CSF rhinorrhea has never been reported in the neurosurgical field.

Conclusion: Spontaneous cerebrospinal fluid rhinorrhea is often treated by surgery, and a transsphenoidal approach repair is the main surgical method used, offering the advantages of less trauma, fewer complications, rapid postoperative recovery, and low recurrence rate.

PubMed Disclaimer

Conflict of interest statement

The authors have no conflicts of interest to disclose.

Figures

Figure 1
Figure 1
Patchy shadow is observed in left ethmoid sinus and sphenoid sinus, upper slope bone is not continuous, and seems to be connected with suprasellar cistern.
Figure 2
Figure 2
Anterior cranial fossa left sieve plate bone seems to be discontinuous, intracranial abnormal signal is connected with left ethmoid sinus.
Figure 3
Figure 3
Arrow refers to the bone defect site after skull 3D imaging.
Figure 4
Figure 4
Nasal septal defect could be observed during surgery.
Figure 5
Figure 5
Slope bone defects.
Figure 6
Figure 6
Expand the fistula into a 1.0×1.0 cm2 bone window.
Figure 7
Figure 7
The order of filling of the surgical repair: fat—sarcoplasm—fibrin glue—fascia lata—surgicel—fibrin glue—nasal septum mucosa flap.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Oleś K, Składzien J, Betlej M, et al. Spontaneous cerebrospinal fluid leak at the clivus. Wideochir Inne Tech Maloinwazyjne 2015;10:593–9. - PMC - PubMed
    1. Fraioli MF, Umana GE, Fiorucci G, et al. Ethmoidal encephalocele associated with cerebrospinal fluid fistula: indications and results of mini-invasive transnasal approach. J Craniofac Surg 2014;25:551–3. - PubMed
    1. Reddy M, Baugnon K. Imaging of Cerebrospinal Fluid Rhinorrhea and Otorrhea. Radiol Clin North Am 2017;55:167–87. - PubMed
    1. Tumturk A, Ulutabanca H, Gokoglu A, et al. The results of the surgical treatment of spontaneous rhinorrhea via craniotomy and the contribution of CT cisternography to the detection of exact leakage side of CSF. Turk Neurosurg 2016;26:699–703. - PubMed
    1. Connor SE. Imaging of skull-base cephalocoeles and cerebrospinal fluid leaks. Clin Radiol 2010;65:832–41. - PubMed

Publication types

MeSH terms