Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2018 Feb 1;378(5):489-490.
doi: 10.1056/NEJMc1716478.

Tolvaptan in Later-Stage Polycystic Kidney Disease

Affiliations
Comment

Tolvaptan in Later-Stage Polycystic Kidney Disease

Vicente E Torres et al. N Engl J Med. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

No potential conflict of interest relevant to this letter was reported.

Comment on

References

    1. Torres VE, Chapman AB, Devuyst O, et al. Tolvaptan in later-stage autosomal dominant polycystic kidney disease. N Engl J Med 2017; 377: 1930–42. - PubMed
    1. Irazabal MV, Torres VE, Hogan MC, et al. Short-term effects of tolvaptan on renal function and volume in patients with autosomal dominant polycystic kidney disease. Kidney Int 2011; 80: 295–301. - PubMed
    1. Takahashi N, Kondo Y, Ito O, Igarashi Y, Omata K, Abe K. Vasopressin stimulates Cl- transport in ascending thin limb of Henle’s loop in hamster. J Clin Invest 1995; 95: 1623–7. - PMC - PubMed
    1. Boertien WE, Meijer E, de Jong PE, et al. Short-term effects of tolvaptan in individuals with autosomal dominant polycystic kidney disease at various levels of kidney function. Am J Kidney Dis 2015; 65: 833–41. - PubMed
    1. Aoyagi T, Izumi Y, Hiroyama M, et al. Vasopressin regulates the renin-angiotensin-aldosterone system via V1a receptors in macula densa cells. Am J Physiol Renal Physiol 2008; 295: F100–F107. - PubMed

LinkOut - more resources