The Importance of Adequately Powered Clinical Studies: Response to Khan et al

Affiliations

¹ From the Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles; the VA Desert Pacific Mental Illness Research, Education, and Clinical Center, Los Angeles; Laughren Psychopharmacology Consulting, Rockville, Md.; and Mallinckrodt Pharmaceuticals, St. Louis.

Comment

Stephen R Marder et al. Am J Psychiatry. 2018.

. 2018 Feb 1;175(2):188-189.

doi: 10.1176/appi.ajp.2017.17091016r.

¹ From the Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles; the VA Desert Pacific Mental Illness Research, Education, and Clinical Center, Los Angeles; Laughren Psychopharmacology Consulting, Rockville, Md.; and Mallinckrodt Pharmaceuticals, St. Louis.

No abstract available

Keywords: Clinical Drug Studies; Other Aspects Of Psychopharmacology.

Comment on

Why Are Innovative Drugs Failing in Phase III?
Marder SR, Laughren T, Romano SJ. Marder SR, et al. Am J Psychiatry. 2017 Sep 1;174(9):829-831. doi: 10.1176/appi.ajp.2017.17040426. Am J Psychiatry. 2017. PMID: 28859511 No abstract available.
The Impact of Underpowered Studies on Clinical Trial Results.
Khan A, Fahl Mar K, Brown WA. Khan A, et al. Am J Psychiatry. 2018 Feb 1;175(2):188. doi: 10.1176/appi.ajp.2017.17091016. Am J Psychiatry. 2018. PMID: 29385825 No abstract available.