Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 2018 Jan 31;11(1):89.
doi: 10.1186/s13104-018-3198-8.

Factors associated with timing of umbilical cord clamping in tertiary hospital of Nepal

Viktoria Nelin  1 , Ashish Kc  1   2 , Ola Andersson  1 , Nisha Rana  1 , Mats Målqvist  3
Affiliations
Clinical Trial

Factors associated with timing of umbilical cord clamping in tertiary hospital of Nepal

Viktoria Nelin et al. BMC Res Notes. .

Abstract

Objective: Delayed umbilical cord clamping (DCC) (≥ 60 s) is recognized to improve iron status and neurodevelopment compared to early umbilical cord clamping. The aim of this study is to identify current umbilical cord clamping practice and factors determining the timing of clamping in a low-resource setting where prevalence of anemia in infants is high.

Results: A cross-sectional study design including 128 observations of clinical practice in a tertiary-level maternity hospital in Kathmandu, Nepal. Overall 48% of infants received DCC. The mean and median cord clamping times were 61 ± 33 and 57 (38-79) s, respectively. Univariate analysis showed that infants born during the night shift were five times more likely to receive DCC (OR 5.6, 95% CI 1.4-38.0). Additionally, infants born after an obstetric complication were 2.5 times more likely to receive DCC (OR 2.5, 95% CI 1.2-5.3), and babies requiring ventilation had a 65% lower likelihood of receiving DCC (OR 0.35, 95% CI 0.13-0.88). Despite the existence of standard protocols for cord clamping and its proven benefit, the lack of uniformity in the timing of cord clamping reveals poor translation of clinical guidelines into clinical practice. Clinical trial registration ISRCTN97846009.

Keywords: Clinical practice; Cord clamping; Nepal; Umbilical cord.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Flow chart of study participants included in this study (MNSC Maternal and Newborn Service Center, LR Labor Room, OT Operation Theater)
See this image and copyright information in PMC

References

    1. Lozoff B, Beard J, Connor J, Barbara F, Georgieff M, Schallert T. Long-lasting neural and behavioral effects of iron deficiency in infancy. Nutr Rev. 2006;64(5 Pt 2):S34–S43. doi: 10.1301/nr.2006.may.S34-S43. - DOI - PMC - PubMed
    1. Radlowski EC, Johnson RW. Perinatal iron deficiency and neurocognitive development. Front Hum Neurosci. 2013;7:585. doi: 10.3389/fnhum.2013.00585. - DOI - PMC - PubMed
    1. Haas JD, Brownlie Tt. Iron deficiency and reduced work capacity: a critical review of the research to determine a causal relationship. J Nutr. 2001;131(2S-2):676S–688S. doi: 10.1093/jn/131.2.676S. - DOI - PubMed
    1. Stevens GA, Finucane MM, De-Regil LM, Paciorek CJ, Flaxman SR, Branca F, Pena-Rosas JP, Bhutta ZA, Ezzati M, Nutrition Impact Model Study G Global, regional, and national trends in haemoglobin concentration and prevalence of total and severe anaemia in children and pregnant and non-pregnant women for 1995–2011: a systematic analysis of population-representative data. Lancet Global Health. 2013;1(1):e16–e25. doi: 10.1016/S2214-109X(13)70001-9. - DOI - PMC - PubMed
    1. Ministry of Health and Population. New Era. ICF Macro. USAID . Nepal demographic and health survey. Kathmandu: New Era; 2011.

Associated data