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Review
. 2018;138(2):191-209.
doi: 10.1248/yakushi.17-00187.

[Stereocontrolled Total Synthesis of Biologically Active Natural Products]

[Article in Japanese]
Susumi Hatakeyama  1
Affiliations
Free article
Review

[Stereocontrolled Total Synthesis of Biologically Active Natural Products]

[Article in Japanese]
Susumi Hatakeyama. Yakugaku Zasshi. 2018.
Free article

Abstract

This review article describes the total syntheses of englerin A, ophiodilactones A and B, marinomycin A, N-methylwelwitindolinone C isothiocyanate, tirandamycins A-D, and tirandalydigin, which possess intriguing biological activities and challenging structures with characteristic ring systems. The focus is on the synthetic methodologies that lead to the highly stereocontrolled assembly of these natural products.

Keywords: natural product; stereocontrolled synthesis; total synthesis.

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