Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2017 Nov 27;9(11):e1884.
doi: 10.7759/cureus.1884.

Paired Ear Creases of the Helix (PECH): A Possible Physical Sign

Affiliations
Case Reports

Paired Ear Creases of the Helix (PECH): A Possible Physical Sign

Pirunthan Pathmarajah et al. Cureus. .

Abstract

Diagonal ear lobe creases, often known as Frank's sign, are a folding in the skin of the ear lobe. Many studies have found an association between diagonal ear lobe creases and coronary artery disease. To our knowledge, this is the first report of paired ear creases of the helix. They may have similar relevance to cardiovascular disease as the diagonal ear lobe creases. We report the case of a 68-year-old South Asian man with coronary artery disease and a diagonal ear lobe crease. On closer inspection of the auricle, he also had ear creases on the helix on the same side. We postulate that diagonal ear lobe creases and paired ear creases of the helix are formed due to pressure during sleep on a hard surface. The pathophysiological association of these creases to coronary artery disease and metabolic syndrome are not well understood. We report a new possible sign: paired ear creases of the helix which may have similar clinical significance as the diagonal ear lobe crease with respect to cardiovascular disease.

Keywords: coronary artery disease; diagonal ear lobe crease; frank's sign; metabolic syndrome; paired ear creases of the helix.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Photograph and diagram of the left ear
(a) Diagonal earlobe crease and paired ear creases of the helix (photograph); (b) Diagonal earlobe crease (D) and paired ear creases of the helix (P) (diagram of photograph)

References

    1. Aural sign of coronary-artery disease. [Nov;2017 ];Frank ST. http://www.nejm.org/doi/full/10.1056/NEJM197308092890622 N Engl J Med. 1973 289:327–328. - PubMed
    1. Diagonal earlobe creases and prognosis in patients with suspected coronary artery disease. [Nov;2018 ];Elliott WJ, Powell LH. http://www.sciencedirect.com/science/article/pii/S0002934397894600. Am J Med. 1996 100:205–211. - PubMed
    1. Bilateral diagonal earlobe crease and coronary artery disease: a significant association. [Nov;2018 ];Evrengul H, Dursunoglu D, Kaftan A, Zoghi M, Tanriverdi H, Zungur M, Kiliç M. https://www.karger.com/Article/Abstract/80847. Dermatology. 2004 209:271–275. - PubMed
    1. Association between earlobe crease and the metabolic syndrome in a cross-sectional study. [Nov;2018 ];Kang EH, Kang HC. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437378/pdf/epih-34-e201200... Epidemiol Health. 2012 34:1–6. - PMC - PubMed

Publication types

LinkOut - more resources