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Review
. 2016 Oct 20:6:121-129.
doi: 10.2147/PTT.S87650. eCollection 2016.

Psoriasis in children

Roxanne Pinson  1 , Bahman Sotoodian  2 , Loretta Fiorillo  2   3
Affiliations
Review

Psoriasis in children

Roxanne Pinson et al. Psoriasis (Auckl). .

Abstract

The clinical presentation, disease associations, and diverse treatment modalities in overcoming the challenges of managing pediatric psoriasis have been extensively summarized in this article. An extensive literature review revealed the differences in presentation of psoriasis during infancy, childhood, and adolescence. We also summarized the latest topical, systemic, and biological modalities in treating recalcitrant psoriasis. The association of psoriasis with juvenile arthritis and obesity and the significant influence of the disease on the children's quality of life were explored. The clinical presentation of psoriasis can evolve during the child's lifespan. While many treatment modalities already exist for treating pediatric psoriasis, some of the new biologics that are approved for adult patients have not been investigated in the pediatric population and no algorithm exists for their use in this population. Large clinical studies in the future will enhance our understanding with regards to their safety and potential implications in pediatric populations.

Keywords: biologics; epidemiology; juvenile arthritis; pediatric; phototherapy; systemic treatment; topical treatment.

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Conflict of interest statement

Disclosure Dr Fiorillo declares a conflict of interest as she is involved with a clinical study on pediatric psoriasis sponsored by Celgene corporation. The authors report no other conflicts of interest in this work.

Figures

Figure 1
Figure 1
Plaque psoriasis involving scrotum, mons pubis, penile shaft, as well as perianal area. Notes: Multiple well-demarcated erythematous plaques over inner thighs as well as over anterior trunk are noted too.
Figure 2
Figure 2
Presence of hyperkeratotic plaques over the top of the scalp as well as periauricle area is noted. Notes: The importance of examination of the pediatric patient while the parents hold the patient is clearly demonstrated here.
Figure 3
Figure 3
Well-demarcated erythematous plaques with fine micaceous scale over periauricular area and crus of helix are noted.
Figure 4
Figure 4
Significant nail pitting and onycholysis are depicted on this image.
See this image and copyright information in PMC

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