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. 2017 Dec 26:6:160.
doi: 10.4103/abr.abr_171_15. eCollection 2017.

Comparison of Nasal Mucociliary Function before and after Septorhinoplasty Surgery Using Saccharin Test

Mostafa Hashemi  1 , Ali Reza Dadgostar  1 , Nezamoddin Berjis  1
Affiliations

Comparison of Nasal Mucociliary Function before and after Septorhinoplasty Surgery Using Saccharin Test

Mostafa Hashemi et al. Adv Biomed Res. .

Abstract

Background: This study was carried out to compare mucociliary function (MCF) of nasal cavity before and after septorhinoplasty surgery by saccharin test.

Materials and methods: This study was carried out on 70 patients who needed septorhinoplasty surgery in Kashani and Alzahra Hospital during 2013-2014 to measure MCF. Saccharin test was performed on the patients before surgery and on three more intervals 1 day, 1 week, and on month after ward and the readings were recorded. Saccharin test is performed by placing saccharin granules on the anterior part of inferior turbinate and the time the patient feels the sweet taste is recorded the normal range is below 30 min.

Results: Mean of test for each time interval was obtained and comparison of measurements was made reading were mean of saccharin test before surgery (7.74 ± 1.65 min) the day after surgery (7.75 ± 1.7 min), on week after surgery (15.04 ± 3.4), and 1 month after surgery (8.49 ± 2.08 min). The readings before surgery did not have statistically significant difference with the readings 1 day after surgery P = 0.99, but comparison of test results at other time intervals were significant (P < 0.001). A relative increase in saccharin test time was seen in a period of 1 month after surgery the rise was more noticeable in the 1st week compared to 1 month after surgery.

Conclusion: This study in the period after septorhinoplasty surgery MCF undergoes slight impairment that gradually progresses to normal values during 1 month after surgery.

Keywords: Mucociliary function; saccharin test; septorhinoplasty.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Mean of saccharin test in four stages
Figure 2
Figure 2
Comparison of saccharin test time of different study stages
See this image and copyright information in PMC

References

    1. Flint PW, Haughey BH, Robbins KT, Thomas JR, Niparko JK, Lund VJ, et al. Cummings Otolaryngology: Head and Neck Surgery. 5th ed. USA maryland: Mosby, Elsevier; 2010. pp. 661–663. 745.
    1. Levine H, Clemente MP. Sinus surgery: Endoscopic and Microscopic Approaches. Germany Stuttgart: Thieme; 2005. pp. 76–9.
    1. Youngs R, Wigand ME. Endoscopic surgery of the paranasal sinuses and anterior skull base. The Journal of Laryngology and Otology. 2009;123:148.
    1. Scadding GK. Investigative Rhinology. London: Taylor & Francis; 2004. pp. 50–52.
    1. Stanley P, MacWilliam L, Greenstone M, Mackay I, Cole P. Efficacy of a saccharin test for screening to detect abnormal mucociliary clearance. Br J Dis Chest. 1984;78:62–5. - PubMed