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Review
. 2017:2017:3512784.
doi: 10.1155/2017/3512784. Epub 2017 Dec 13.

Effect of Gonadotropin Types and Indications on Homologous Intrauterine Insemination Success: A Study from 1251 Cycles and a Review of the Literature

Rosalie Cabry-Goubet  1   2 , Florence Scheffler  1   2 , Naima Belhadri-Mansouri  1 , Stephanie Belloc  3 , Emmanuelle Lourdel  1 , Aviva Devaux  1   2 , Hickmat Chahine  4 , Jacques De Mouzon  4 , Henri Copin  1 , Moncef Benkhalifa  1   2
Affiliations
Review

Effect of Gonadotropin Types and Indications on Homologous Intrauterine Insemination Success: A Study from 1251 Cycles and a Review of the Literature

Rosalie Cabry-Goubet et al. Biomed Res Int. 2017.

Abstract

Objective: To evaluate the IUI success factors relative to controlled ovarian stimulation (COS) and infertility type, this retrospective cohort study included 1251 couples undergoing homologous IUI.

Results: We achieved 13% clinical pregnancies and 11% live births. COS and infertility type do not have significant effect on IUI clinical outcomes with unstable intervention of various couples' parameters, including the female age, the IUI attempt rank, and the sperm quality.

Conclusion: Further, the COS used seemed a weak predictor for IUI success; therefore, the indications need more discussion, especially in unexplained infertility cases involving various factors. Indeed, the fourth IUI attempt, the female age over 40 years, and the total motile sperm count <5 × 106 were critical in decreasing the positive clinical outcomes of IUI. Those parameter cut-offs necessitate a larger analysis to give infertile couples more chances through IUI before carrying out other ART techniques.

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References

    1. Boivin J., Bunting L., Collins J. A., Nygren K. G. International estimates of infertility prevalence and treatment-seeking: potential need and demand for infertility medical care. Human Reproduction. 2007;22(6):1506–1512. doi: 10.1093/humrep/dem046. - DOI - PubMed
    1. Bushnik T., Cook J. L., Yuzpe A. A., Tough S., Collins J. Estimating the prevalence of infertility in Canada. Human Reproduction. 2012;27(3):738–746. doi: 10.1093/humrep/der465. - DOI - PMC - PubMed
    1. Thoma M. E., McLain A. C., Louis J. F., et al. Prevalence of infertility in the United States as estimated by the current duration approach and a traditional constructed approach. Fertility and Sterility. 2013;99(5):1324–1331.e1. doi: 10.1016/j.fertnstert.2012.11.037. - DOI - PMC - PubMed
    1. Slama R., Hansen O. K. H., Ducot B., et al. Estimation of the frequency of involuntary infertility on a nation-wide basis. Human Reproduction. 2012;27(5):1489–1498. doi: 10.1093/humrep/des070. - DOI - PubMed
    1. The ESHRE Capri Workshop Group. Intrauterine insemination. Human Reproduction Update. 2009;15(3):265–277. doi: 10.1093/humupd/dmp003. - DOI - PubMed

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