Induction of fragile sites in fibroblasts
- PMID: 2939714
- PMCID: PMC1684789
Induction of fragile sites in fibroblasts
Abstract
A simple, reliable method for the induction of folate-sensitive fragile sites, including the fragile X, in fibroblasts is described. The method involves only the addition of 600 mg/l thymidine to cultures 24 hrs before they are harvested.
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