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Comparative Study
. 2018 Feb;26(1):132-135.
doi: 10.7534/j.issn.1009-2137.2018.01.022.

[Comparison of Diagnosis Values of CD64 Infection Index, CRP, PCT and NEU% in the Leukemia Complicated with Bacterial Infection]

[Article in Chinese]
Xiao-Yan Guo  1 , Yun-Kai Kang  1 , Shu-Xia Guo  2
Affiliations
Comparative Study

[Comparison of Diagnosis Values of CD64 Infection Index, CRP, PCT and NEU% in the Leukemia Complicated with Bacterial Infection]

[Article in Chinese]
Xiao-Yan Guo et al. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2018 Feb.

Abstract

Objective: To compare the diagnostic values of CD64 infection index, C-reactive protein (CRP), procalcitonin (PCT) and the percentage of neutrophils (NEU%) in leukemia patients complicated with bacterial infection.

Methods: Sixty cases of leukemia complicated with bacterial infection (combination with infection group), 60 cases of leukemia without bacterial infection (non-combination with infection group) and 60 cases of healthy persons (control group) were selected in our hospital. CD64 infection index, CRP, PCT and NEU% were detected in the 3 group.

Results: CD64 infection index, CRP, PCT and NEU% in combination with infection group were significantly higher than those in the non-combination with infection group and also significantly higher than those in the control group (all P<0.05). The CD64 infection index, CRP, PCT and NEU% in the non-combination with infection group were significantly higher than those in the control group (all P<0.05). The sensitivities of CD64, CRP, PCT and NEU% in the diagnosis of the leukemia with bacterial infection were 71.06%, 84.86%, 66.93% and 59.25% respectively, and the specificities of CD64, CRP, PCT and NEU% were 91.46%, 75.94%, 88.79% and 85.36% respectively.

Conclusion: Compared with CRP, PCT and NEU%, CD64 infection index for diagnosis of leukemia complicated with bacterial infection has higher specificity, which is helpful for the early diagnosis of the disease.

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